C-RAY Achieves Breakthrough in Medical Isotope Production with China's First Fully Automated Zr-89 Process
Leveraging proprietary isotope production technology and customized automated facilities, C-Ray Therapeutics has successfully implemented China's first end-to-end automated production process for Zirconium-89 (⁸⁹Zr) – positioning itself among the few Chinese suppliers capable of stable ⁸⁹Zr provision.
Technical Background:
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Positron Emission Tomography (PET) is a rapidly advancing molecular imaging technology renowned for its high sensitivity and quantitative capabilities.
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Molecular probes are prerequisites for molecular imaging. While Fluorine-18 (¹⁸F) is widely used for its excellent imaging properties, its short half-life (t₁/₂ = 109 min) limits applications involving macromolecular bioactive agents (e.g., antibodies) that require extended imaging windows.
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Zirconium-89 (⁸⁹Zr) emerges as an ideal PET immunoimaging isotope with:
▶ 78.4-hour half-life (aligns with biological clearance of monoclonal antibodies)
▶ 0.897 MeV average positron energy
▶ Optimized pharmacokinetic compatibility for antibody-based tracers
Strategic Significance:
This milestone completes a critical component of Tongrui Biotech's autonomous medical isotope supply chain. Moving forward, we will provide domestic and international partners with:
✓ Consistent, controllable ⁸⁹Zr quality
✓ Full compliance with Group Standards